Much like how hemp has specific benefits, hemp isolate has been shown to provide a range of unique benefits. Hemp isolate has a reputation for helping with sleep, and research using animal models and recent studies working with human participants has supported this reputation. In a study by Kaufmann (2021), administration of hemp isolate over the course of 7 days resulted in improvements in self-reported sleep outcomes. In another study (Bonn-Miller et al., 2024), administration of hemp isolate in isolation improved sleep outcomes, particularly through reducing sleep disturbance throughout the night and the number of nighttime awakenings. Importantly, this study also included doses of hemp isolate (20 mg) paired with differing doses of hemp extract (10, 20, and 100 mg). Twenty milligrams of hemp isolate alone reduced nighttime awakening and sleep disturbance compared to placebo. The addition of varying doses of hemp did not improve sleep quality. Based on this study, it appears that when pairing hemp isolate and hemp together, they are less helpful for sleep than when either is used in isolation.

The short answer to both questions is the same as it is for full-spectrum, “It depends.” It depends on many factors such as the starting point of your body’s systems, as well as the concentration of hemp isolate you’re using. The bottom line is that hemp isolate may affect everyone a little differently and work gradually over time. Dietary supplements like Charlotte’s Web™ hemp extract products are crafted to work with your body naturally. Results come by way of steady use, which will make beneficial changes more sustainable.